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3D investigation shows walls and wall-like structures around human germinal centres, probably regulating T- and B-cell entry and exit

This study deals with 3D laser investigation on the border between the human lymph node T-zone and germinal centre. Only a few T-cells specific for antigen selected B-cells are allowed to enter germinal centres. This selection process is guided by sinus structures, chemokine gradients and inherent m...

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Detalles Bibliográficos
Autores principales: Thomos, Miguel, Wurzel, Patrick, Scharf, Sonja, Koch, Ina, Hansmann, Martin-Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654765/
https://www.ncbi.nlm.nih.gov/pubmed/33170900
http://dx.doi.org/10.1371/journal.pone.0242177