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Static all-atom energetic mappings of the SARS-Cov-2 spike protein and dynamic stability analysis of “Up” versus “Down” protomer states

The SARS-CoV-2 virion responsible for the current world-wide pandemic COVID-19 has a characteristic Spike protein (S) on its surface that embellishes both a prefusion state and fusion state. The prefusion Spike protein (S) is a large trimeric protein where each protomer may be in a so-called Up stat...

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Detalles Bibliográficos
Autores principales: Peters, Michael H., Bastidas, Oscar, Kokron, Daniel S., Henze, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654774/
https://www.ncbi.nlm.nih.gov/pubmed/33170884
http://dx.doi.org/10.1371/journal.pone.0241168