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Renoprotective and haemodynamic effects of adiponectin and peroxisome proliferator-activated receptor agonist, pioglitazone, in renal vasculature of diabetic Spontaneously hypertensive rats

Pioglitazone, a therapeutic drug for diabetes, possesses full PPAR-γ agonist activity and increase circulating adiponectin plasma concentration. Plasma adiponectin concentration decreases in hypertensive patients with renal dysfunctions. Present study investigated the reno-protective, altered excret...

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Detalles Bibliográficos
Autores principales: Afzal, Sheryar, Abdul Sattar, Munavvar, Johns, Edward James, Eseyin, Olorunfemi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654782/
https://www.ncbi.nlm.nih.gov/pubmed/33170841
http://dx.doi.org/10.1371/journal.pone.0229803