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High-mannose type N-glycans with core fucosylation and complex-type N-glycans with terminal neuraminic acid residues are unique to porcine islets

OBJECTIVES: Islet transplantation is an emerging treatment option for type 1 diabetes but its application is limited by the shortage of human pancreas donors. Characterization of the N- and O-glycan surface antigens that vary between human and genetically engineered porcine islet donors could shed l...

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Detalles Bibliográficos
Autores principales: Nanno, Yoshihide, Shajahan, Asif, Sonon, Roberto N., Azadi, Parastoo, Hering, Bernhard J., Burlak, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654812/
https://www.ncbi.nlm.nih.gov/pubmed/33170858
http://dx.doi.org/10.1371/journal.pone.0241249