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Differential Involvement of the Locus Coeruleus in Early- and Late-Onset Alzheimer’s Disease: A Potential Mechanism of Clinical Differences?

Early-onset Alzheimer’s disease (EOAD) has been associated with an increased likelihood of atypical clinical manifestations such as attentional impairment, yet the cause of this heterogeneity remains unclear. The locus coeruleus (LC) is implicated early in Alzheimer’s disease pathology and is associ...

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Detalles Bibliográficos
Autores principales: Bolton, Corey J., Tam, Joyce W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654926/
https://www.ncbi.nlm.nih.gov/pubmed/33173930
http://dx.doi.org/10.1101/2020.11.01.20224139