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Transgenic goats producing an improved version of cetuximab in milk

Therapeutic monoclonal antibodies (mAbs) represent one of the most important classes of pharmaceutical proteins to treat human diseases. Most are produced in cultured mammalian cells which is expensive, limiting their availability. Goats, striking a good balance between a relatively short generation...

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Detalles Bibliográficos
Autores principales: Laible, Götz, Cole, Sally, Brophy, Brigid, Maclean, Paul, How Chen, Li, Pollock, Dan P., Cavacini, Lisa, Fournier, Nathalie, De Romeuf, Christophe, Masiello, Nicholas C., Gavin, William G., Wells, David N., Meade, Harry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655094/
https://www.ncbi.nlm.nih.gov/pubmed/33205005
http://dx.doi.org/10.1096/fba.2020-00059