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Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

Contrary to dogma, evolutionarily young and dynamic genes can encode essential functions. We find that evolutionarily dynamic ZAD-ZNF genes, which encode the most abundant class of insect transcription factors, are more likely to encode essential functions in Drosophila melanogaster than ancient, co...

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Detalles Bibliográficos
Autores principales: Kasinathan, Bhavatharini, Colmenares, Serafin U, McConnell, Hannah, Young, Janet M, Karpen, Gary H, Malik, Harmit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655104/
https://www.ncbi.nlm.nih.gov/pubmed/33169670
http://dx.doi.org/10.7554/eLife.63368