Cohesin residency determines chromatin loop patterns

The organization of chromatin into higher order structures is essential for chromosome segregation, the repair of DNA-damage, and the regulation of gene expression. Using Micro-C XL to detect chromosomal interactions, we observed the pervasive presence of cohesin-dependent loops with defined positio...

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Detalles Bibliográficos
Autores principales: Costantino, Lorenzo, Hsieh, Tsung-Han S, Lamothe, Rebecca, Darzacq, Xavier, Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655110/
https://www.ncbi.nlm.nih.gov/pubmed/33170773
http://dx.doi.org/10.7554/eLife.59889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655110/
https://www.ncbi.nlm.nih.gov/pubmed/33170773
http://dx.doi.org/10.7554/eLife.59889

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