Cargando…

The Relationship Between Actin Cytoskeleton and Membrane Transporters in Cisplatin Resistance of Cancer Cells

Cisplatin [cis-diamminedichloroplatinum (II)] is a platinum-based anticancer drug widely used for the treatment of various cancers. It forms interstrand and intrastrand cross-linking with DNA and block DNA replication, resulting in apoptosis. On the other hand, intrinsic and acquired cisplatin resis...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimizu, Takahiro, Fujii, Takuto, Sakai, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655133/
https://www.ncbi.nlm.nih.gov/pubmed/33195280
http://dx.doi.org/10.3389/fcell.2020.597835