Stress-induced p53 drives BAG5 cochaperone expression to control α-synuclein aggregation in Parkinson's disease

Parkinson’s disease (PD) is a common neurodegenerative disorder with the pathological hallmark of α-synuclein aggregation. Dysregulation of α-synuclein homeostasis caused by aging, genetic, and environmental factors underlies the pathogenesis of PD. While chaperones are essential for proteostasis, w...

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Detalles Bibliográficos
Autores principales: Chen, Huan-Yun, Lin, Chin-Hsien, Teng, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655153/
https://www.ncbi.nlm.nih.gov/pubmed/33085644
http://dx.doi.org/10.18632/aging.103998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655153/
https://www.ncbi.nlm.nih.gov/pubmed/33085644
http://dx.doi.org/10.18632/aging.103998

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