MicroRNA-143 sensitizes acute myeloid leukemia cells to cytarabine via targeting ATG7- and ATG2B-dependent autophagy

Targeting autophagy holds promise to enhance chemosensitivity in acute myeloid leukemia (AML). MicroRNA-143 (miR-143) has been found to suppress autophagy, however, it is not clear whether miR-143 augments cytarabine cytotoxicity in AML. Here, we report that cytarabine treatment reduces miR-143 expr...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Kang, Jianmin, Liu, Ling, Chen, Lulu, Ren, Saisai, Tao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655171/
https://www.ncbi.nlm.nih.gov/pubmed/33077697
http://dx.doi.org/10.18632/aging.103614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655171/
https://www.ncbi.nlm.nih.gov/pubmed/33077697
http://dx.doi.org/10.18632/aging.103614

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