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GDF11 induces mild hepatic fibrosis independent of metabolic health

Background & aims: Growth Differentiation Factor 11 (GDF11) is an anti-aging factor, yet its role in liver diseases is not established. We evaluated the role of GDF11 in healthy conditions and in the transition from non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH...

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Detalles Bibliográficos
Autores principales: Frohlich, Jan, Kovacovicova, Kristina, Mazza, Tommaso, Emma, Maria R., Cabibi, Daniela, Foti, Michelangelo, Sobolewski, Cyril, Oben, Jude A., Peyrou, Marion, Villarroya, Francesc, Soresi, Maurizio, Rezzani, Rita, Cervello, Melchiorre, Bonomini, Francesca, Alisi, Anna, Vinciguerra, Manlio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655202/
https://www.ncbi.nlm.nih.gov/pubmed/33126224
http://dx.doi.org/10.18632/aging.104182