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SNCA Rep1 microsatellite length influences non-motor symptoms in early Parkinson’s disease

Long alpha-synuclein gene (SNCA) promoter (Rep1) allele-carriers are linked to higher risk for Parkinson’s disease (PD) and faster motor progression. Non-motor symptoms including autonomic, neuropsychiatric, and sleep disorders are common in PD. However, the relationship between SNCA Rep1 microsatel...

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Detalles Bibliográficos
Autores principales: Yong, Alisa CW, Tan, Yi Jayne, Zhao, Yi, Lu, Zhonghao, Ng, Ebonne YL, Ng, Samuel YE, Chia, Nicole SY, Choi, Xinyi, Heng, Dede, Neo, Shermyn, Xu, Zheyu, Tay, Kay Yaw, Au, Wing Lok, Tan, Eng-King, Tan, Louis CS, Ng, Adeline SL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655210/
https://www.ncbi.nlm.nih.gov/pubmed/33082300
http://dx.doi.org/10.18632/aging.104111