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Oxidized LDL Disrupts Metabolism and Inhibits Macrophage Survival by Activating a miR-9/Drp1/Mitochondrial Fission Signaling Pathway

Mitochondrial dysfunction is associated with macrophage damage, but the role of mitochondrial fission in macrophage cholesterol metabolism is not fully understood. In this study, we explored the influences of miR-9 and mitochondrial fission on macrophage viability and cholesterol metabolism. Macroph...

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Detalles Bibliográficos
Autores principales: Xin, Ting, Lu, Chengzhi, Zhang, Jing, Wen, Jiaxin, Yan, Shuangbin, Li, Chao, Zhang, Feng, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655251/
https://www.ncbi.nlm.nih.gov/pubmed/33204400
http://dx.doi.org/10.1155/2020/8848930