Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells

1,2-unsaturated pyrrolizidine alkaloids (PAs) are natural plant constituents comprising more than 600 different structures. A major source of human exposure is thought to be cross-contamination of food, feed and phytomedicines with PA plants. In humans, laboratory and farm animals, certain PAs exert...

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Detalles Bibliográficos
Autores principales: Rutz, Lukas, Gao, Lan, Küpper, Jan-Heiner, Schrenk, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655576/
https://www.ncbi.nlm.nih.gov/pubmed/32910235
http://dx.doi.org/10.1007/s00204-020-02895-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655576/
https://www.ncbi.nlm.nih.gov/pubmed/32910235
http://dx.doi.org/10.1007/s00204-020-02895-z

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