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Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells
1,2-unsaturated pyrrolizidine alkaloids (PAs) are natural plant constituents comprising more than 600 different structures. A major source of human exposure is thought to be cross-contamination of food, feed and phytomedicines with PA plants. In humans, laboratory and farm animals, certain PAs exert...
Autores principales: | Rutz, Lukas, Gao, Lan, Küpper, Jan-Heiner, Schrenk, Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655576/ https://www.ncbi.nlm.nih.gov/pubmed/32910235 http://dx.doi.org/10.1007/s00204-020-02895-z |
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