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Structural basis of ion transport and inhibition in ferroportin

Ferroportin is an iron exporter essential for releasing cellular iron into circulation. Ferroportin is inhibited by a peptide hormone, hepcidin. In humans, mutations in ferroportin lead to ferroportin diseases that are often associated with accumulation of iron in macrophages and symptoms of iron de...

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Detalles Bibliográficos
Autores principales: Pan, Yaping, Ren, Zhenning, Gao, Shuai, Shen, Jiemin, Wang, Lie, Xu, Zhichun, Yu, Ye, Bachina, Preetham, Zhang, Hanzhi, Fan, Xiao, Laganowsky, Arthur, Yan, Nieng, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655804/
https://www.ncbi.nlm.nih.gov/pubmed/33173040
http://dx.doi.org/10.1038/s41467-020-19458-6