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Integrating single-cell RNA-seq and imaging with SCOPE-seq2

Live cell imaging allows direct observation and monitoring of phenotypes that are difficult to infer from transcriptomics. However, existing methods for linking microscopy and single-cell RNA-seq (scRNA-seq) have limited scalability. Here, we describe an upgraded version of Single Cell Optical Pheno...

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Detalles Bibliográficos
Autores principales: Liu, Zhouzerui, Yuan, Jinzhou, Lasorella, Anna, Iavarone, Antonio, Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655825/
https://www.ncbi.nlm.nih.gov/pubmed/33173156
http://dx.doi.org/10.1038/s41598-020-76599-w