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Lifetime encoding in flow cytometry for bead-based sensing of biomolecular interaction

To demonstrate the potential of time-resolved flow cytometry (FCM) for bioanalysis, clinical diagnostics, and optically encoded bead-based assays, we performed a proof-of-principle study to detect biomolecular interactions utilizing fluorescence lifetime (LT)-encoded micron-sized polymer beads beari...

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Detalles Bibliográficos
Autores principales: Kage, Daniel, Hoffmann, Katrin, Borcherding, Heike, Schedler, Uwe, Resch-Genger, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655863/
https://www.ncbi.nlm.nih.gov/pubmed/33173064
http://dx.doi.org/10.1038/s41598-020-76150-x