A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner

Cytoplasmic dynein-1 (dynein) is the motor responsible for most retrograde transport of cargoes along microtubules in eukaryotic cells, including organelles, mRNA and viruses. Cargo selectivity and activation of processive motility depend on a group of so-called “activating adaptors” that link dynei...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, In-Gyun, Cason, Sydney E., Alqassim, Saif S., Holzbaur, Erika L. F., Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655957/
https://www.ncbi.nlm.nih.gov/pubmed/33173051
http://dx.doi.org/10.1038/s41467-020-19538-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655957/
https://www.ncbi.nlm.nih.gov/pubmed/33173051
http://dx.doi.org/10.1038/s41467-020-19538-7

Ejemplares similares