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Synthesis of the Hydroxamate Siderophore N(α)-Methylcoprogen B in Scedosporium apiospermum Is Mediated by sidD Ortholog and Is Required for Virulence

Scedosporium species rank second among the filamentous fungi capable to colonize chronically the respiratory tract of patients with cystic fibrosis (CF). Nevertheless, there is little information on the mechanisms underpinning their virulence. Iron acquisition is critical for the growth and pathogen...

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Detalles Bibliográficos
Autores principales: Le Govic, Yohann, Havlíček, Vladimir, Capilla, Javier, Luptáková, Dominika, Dumas, Dayana, Papon, Nicolas, Le Gal, Solène, Bouchara, Jean-Philippe, Vandeputte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655970/
https://www.ncbi.nlm.nih.gov/pubmed/33194829
http://dx.doi.org/10.3389/fcimb.2020.587909