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PD-L1过表达对CLL-1 CAR-T细胞抗急性髓系白血病作用的影响

OBJECTIVE: To investigate the effects of programmed death receptor ligand 1(PD-L1)on CLL-1 CAR-T against acute myeloid leukemia(AML). METHODS: In this experiment, the PD-L1 expression vector was constructed, and then the lentivirus vector was packaged by three-plasmid packaging system. THP-1 monoclo...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656066/
https://www.ncbi.nlm.nih.gov/pubmed/33190440
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2020.10.007