Cargando…

Thiostrepton and miR-216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1

Osteosarcoma is a common primary bone cancer that there are currently no effective treatment strategies for. Forkhead box M1 (FoxM1) is key in the development of osteosarcoma, and microRNA (miR)-216b serves an antitumor role by targeting FoxM1. Moreover, thiostrepton (TST), a natural thiazole antibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Xiaobing, Xiao, Wenyu, Shen, Juexin, Lian, Hui, Lu, Yi, Liu, Xianmiao, Gu, Jisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656114/
https://www.ncbi.nlm.nih.gov/pubmed/33193851
http://dx.doi.org/10.3892/ol.2020.12254