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Thiostrepton and miR-216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1
Osteosarcoma is a common primary bone cancer that there are currently no effective treatment strategies for. Forkhead box M1 (FoxM1) is key in the development of osteosarcoma, and microRNA (miR)-216b serves an antitumor role by targeting FoxM1. Moreover, thiostrepton (TST), a natural thiazole antibi...
Autores principales: | Cai, Xiaobing, Xiao, Wenyu, Shen, Juexin, Lian, Hui, Lu, Yi, Liu, Xianmiao, Gu, Jisheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656114/ https://www.ncbi.nlm.nih.gov/pubmed/33193851 http://dx.doi.org/10.3892/ol.2020.12254 |
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