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Haplotype architecture of the Alzheimer's risk in the APOE region via co‐skewness

INTRODUCTION: As a multifactorial polygenic disorder, Alzheimer's disease (AD) can be associated with complex haplotypes or compound genotypes. METHODS: We examined associations of 4960 single nucleotide polymorphism (SNP) triples, comprising 32 SNPs from five genes in the apolipoprotein E gene...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Philipp, Ian, Loika, Yury, He, Liang, Culminskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656174/
https://www.ncbi.nlm.nih.gov/pubmed/33204816
http://dx.doi.org/10.1002/dad2.12129