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Haplotype architecture of the Alzheimer's risk in the APOE region via co‐skewness
INTRODUCTION: As a multifactorial polygenic disorder, Alzheimer's disease (AD) can be associated with complex haplotypes or compound genotypes. METHODS: We examined associations of 4960 single nucleotide polymorphism (SNP) triples, comprising 32 SNPs from five genes in the apolipoprotein E gene...
Autores principales: | Kulminski, Alexander M., Philipp, Ian, Loika, Yury, He, Liang, Culminskaya, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656174/ https://www.ncbi.nlm.nih.gov/pubmed/33204816 http://dx.doi.org/10.1002/dad2.12129 |
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