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Experimental inoculation of CD11c(+) B1 lymphocytes, CD68(+) macrophages, or platelet-rich plasma from scrapie-infected sheep into susceptible sheep results in variable infectivity

Many studies have demonstrated prion infectivity in whole blood and blood components in a variety of transmissible spongiform encephalopathies of livestock and rodents, and variant Creutzfeldt–Jakob disease in humans, as well as an association between pathogenic prion protein (PrP(Sc)) and different...

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Detalles Bibliográficos
Autores principales: Mammadova, Najiba, Cassmann, Eric D., Moore, S. Jo, Nicholson, Eric M., Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656192/
https://www.ncbi.nlm.nih.gov/pubmed/33195984
http://dx.doi.org/10.1099/acmi.0.000155