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Disruption of estradiol regulation of orexin neurons: a novel mechanism in excessive ventilatory response to CO(2) inhalation in a female rat model of panic disorder

Panic disorder (PD) is ~2 times more frequent in women. An excessive ventilatory response to CO(2) inhalation is more likely during the premenstrual phase. While ovarian hormones appear important in the pathophysiology of PD, their role remains poorly understood as female animals are rarely used in...

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Detalles Bibliográficos
Autores principales: Tenorio-Lopes, Luana, Fournier, Stéphanie, Henry, Mathilde S., Bretzner, Frédéric, Kinkead, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656265/
https://www.ncbi.nlm.nih.gov/pubmed/33173029
http://dx.doi.org/10.1038/s41398-020-01076-x