Dichotomous Impact of Myc on rRNA Gene Activation and Silencing in B Cell Lymphomagenesis

SIMPLE SUMMARY: B cell lymphomas mostly arise from malignant transformation of mature B cells and are typically driven by elevated levels of the oncoprotein Myc. Myc is a transcription factor regulating many protein-coding genes as well as the multicopy genes encoding ribosomal RNA (rRNA). The aim o...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Gaurav, Eberhardt, Alexander Otto, Lange, Lisa, Winkler, René, Hoffmann, Steve, Kosan, Christian, Bierhoff, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656300/
https://www.ncbi.nlm.nih.gov/pubmed/33081395
http://dx.doi.org/10.3390/cancers12103009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656300/
https://www.ncbi.nlm.nih.gov/pubmed/33081395
http://dx.doi.org/10.3390/cancers12103009

Ejemplares similares