Cargando…

Dichotomous Impact of Myc on rRNA Gene Activation and Silencing in B Cell Lymphomagenesis

SIMPLE SUMMARY: B cell lymphomas mostly arise from malignant transformation of mature B cells and are typically driven by elevated levels of the oncoprotein Myc. Myc is a transcription factor regulating many protein-coding genes as well as the multicopy genes encoding ribosomal RNA (rRNA). The aim o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joshi, Gaurav, Eberhardt, Alexander Otto, Lange, Lisa, Winkler, René, Hoffmann, Steve, Kosan, Christian, Bierhoff, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656300/ https://www.ncbi.nlm.nih.gov/pubmed/33081395 http://dx.doi.org/10.3390/cancers12103009

Ejemplares similares

Mnt modulates Myc-driven lymphomagenesis
por: Campbell, Kirsteen J, et al.
Publicado: (2017)

Role of MYC in B Cell Lymphomagenesis
por: Korać, Petra, et al.
Publicado: (2017)

Myc suppression of Nfkb2 accelerates lymphomagenesis
por: Keller, Ulrich, et al.
Publicado: (2010)

Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis
por: Mathsyaraja, Haritha, et al.
Publicado: (2019)

FoxO3 suppresses Myc-driven lymphomagenesis
por: Vandenberg, C J, et al.
Publicado: (2016)

Lessons from Using Genetically Engineered Mouse Models of MYC-Induced Lymphoma
por: Winkler, René, et al.
Publicado: (2022)

Myc Oncogene-Induced Genomic Instability: DNA Palindromes in Bursal Lymphomagenesis
por: Neiman, Paul E., et al.
Publicado: (2008)

Insights about MYC and Apoptosis in B-Lymphomagenesis: An Update from Murine Models
por: Vecchio, Eleonora, et al.
Publicado: (2020)

Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis
por: Tanaskovic, Nina, et al.
Publicado: (2022)

Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis
por: Potts, Margaret A., et al.
Publicado: (2023)

Activating and sustaining c-Myc by depletion of miR-144/451 gene locus contributes to B-lymphomagenesis
por: Ding, Lan, et al.
Publicado: (2017)

Epigenetic Erosion in Adult Stem Cells: Drivers and Passengers of Aging
por: Kosan, Christian, et al.
Publicado: (2018)

Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning
por: Zhao, Zhongliang, et al.
Publicado: (2016)

A Role for E2F Activities in Determining the Fate of Myc-Induced Lymphomagenesis
por: Rempel, Rachel E., et al.
Publicado: (2009)

The IgH 3′ regulatory region influences lymphomagenesis in Igλ-Myc mice
por: Saad, Faten, et al.
Publicado: (2015)

The IgH 3’ regulatory region and c-myc-induced B-cell lymphomagenesis
por: Ghazzaui, Nour, et al.
Publicado: (2016)

Germinal Centre B Cell Functions and Lymphomagenesis: Circuits Involving MYC and MicroRNAs
por: Robaina, Marcela Cristina, et al.
Publicado: (2019)

IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3
por: Petrenko, Oleksi, et al.
Publicado: (2021)

Immunosenescence and lymphomagenesis
por: Mancuso, Salvatrice, et al.
Publicado: (2018)

EBV and Lymphomagenesis
por: Sausen, Daniel G., et al.
Publicado: (2023)

Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells
por: Sander, Sandrine, et al.
Publicado: (2012)

Cellular redox homeostasis maintained by malic enzyme 2 is essential for MYC-driven T cell lymphomagenesis
por: Li, Wei, et al.
Publicado: (2023)

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation
por: Scott, Clare L., et al.
Publicado: (2004)

Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons
por: Kiryk, Anna, et al.
Publicado: (2013)

Corticostriatal Projection Neurons – Dichotomous Types and Dichotomous Functions
por: Reiner, Anton, et al.
Publicado: (2010)

Epigenetic Silencing of Nucleolar rRNA Genes in Alzheimer's Disease
por: Pietrzak, Maciej, et al.
Publicado: (2011)

Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis
por: Grabow, S, et al.
Publicado: (2016)

The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model
por: Amin, Rada, et al.
Publicado: (2014)

IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis
por: Vecchio, Eleonora, et al.
Publicado: (2019)

Latent membrane proteins from EBV differentially target cellular pathways to accelerate MYC-induced lymphomagenesis
por: Ikeda, Masato, et al.
Publicado: (2022)

Virus-Associated Lymphomagenesis
por: Tarantul, V. Z.
Publicado: (2006)

A deficiency in Mdm2 binding protein (MTBP) inhibits Myc-induced B cell proliferation and lymphomagenesis
por: Odvody, Jessica, et al.
Publicado: (2010)

Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis
por: Iotti, Giorgio, et al.
Publicado: (2012)

Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a Myc/p53-Dependent Bottleneck in Lymphomagenesis
por: Huser, Camille A., et al.
Publicado: (2014)

Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
por: Ferrad, Melissa, et al.
Publicado: (2020)

TET2 deficiency reprograms the germinal center B cell epigenome and silences genes linked to lymphomagenesis
por: Rosikiewicz, Wojciech, et al.
Publicado: (2020)

Lymphomagenesis predictors and related pathogenesis
por: Ruiz-Ordoñez, Ingrid, et al.
Publicado: (2021)

The intelligibility of r or r(2) as an effect size statistic: dichotomous variables
por: Trafimow, David
Publicado: (2015)

Loss of RIPK3 does not impact MYC-driven lymphomagenesis or chemotherapeutic drug-induced killing of malignant lymphoma cells
por: Thijssen, Rachel, et al.
Publicado: (2020)

Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
por: Winkler, René, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2tk1n3tic3tfr94oc30or3tcpi