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Effects of Naturally Occurring Mutations in Bovine Leukemia Virus 5′-LTR and Tax Gene on Viral Transcriptional Activity

Bovine leukemia virus (BLV) is a deltaretrovirus infecting bovine B cells and causing enzootic bovine leucosis (EBL). The long terminal repeat (LTR) plays an indispensable role in viral gene expression. The BLV Tax protein acts as the main transactivator of LTR-driven transcription of BLV viral gene...

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Detalles Bibliográficos
Autores principales: Pluta, Aneta, Willems, Luc, Douville, Renée N., Kuźmak, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656303/
https://www.ncbi.nlm.nih.gov/pubmed/33066207
http://dx.doi.org/10.3390/pathogens9100836