An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells

Synthetic biology has the potential to bring forth advanced genetic devices for applications in healthcare and biotechnology. However, accurately predicting the behavior of engineered genetic devices remains difficult due to lack of modularity, wherein a device’s output does not depend only on its i...

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Detalles Bibliográficos
Autores principales: Jones, Ross D., Qian, Yili, Siciliano, Velia, DiAndreth, Breanna, Huh, Jin, Weiss, Ron, Del Vecchio, Domitilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656454/
https://www.ncbi.nlm.nih.gov/pubmed/33173034
http://dx.doi.org/10.1038/s41467-020-19126-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656454/
https://www.ncbi.nlm.nih.gov/pubmed/33173034
http://dx.doi.org/10.1038/s41467-020-19126-9

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