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An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells
Synthetic biology has the potential to bring forth advanced genetic devices for applications in healthcare and biotechnology. However, accurately predicting the behavior of engineered genetic devices remains difficult due to lack of modularity, wherein a device’s output does not depend only on its i...
Autores principales: | Jones, Ross D., Qian, Yili, Siciliano, Velia, DiAndreth, Breanna, Huh, Jin, Weiss, Ron, Del Vecchio, Domitilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656454/ https://www.ncbi.nlm.nih.gov/pubmed/33173034 http://dx.doi.org/10.1038/s41467-020-19126-9 |
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