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Fate and functional roles of Prominin 1(+) cells in liver injury and cancer

Prominin 1 (PROM1) is one of a few clinically relevant progenitor markers in human alcoholic hepatitis (AH) and hepatocellular carcinoma (HCC), and mouse liver tumor initiating stem cell-like cells (TICs). However, the origin, fate and functions of PROM1(+) cells in AH and HCC are unknown. Here we s...

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Detalles Bibliográficos
Autores principales: Wu, Raymond, Pan, Stephanie, Chen, Yibu, Nakano, Yasuhiro, Li, Meng, Balog, Steven, Tsukamoto, Hidekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656457/
https://www.ncbi.nlm.nih.gov/pubmed/33173221
http://dx.doi.org/10.1038/s41598-020-76458-8