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Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions

The Chimera antigen receptor (CAR)-T cell therapy has gained great success in the clinic. However, there are still major challenges for its wider applications in a variety of cancer types including lack of effectiveness due to the highly complex tumor microenvironment, and the forbiddingly high cost...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Tian, Lin, Dai, Xiaoyang, Yu, Hua, Wang, Jiajia, Lei, Anhua, Zhu, Mengmeng, Xu, Jianpo, Zhao, Wei, Zhu, Yuqing, Sun, Zhen, Zhang, Hao, Hu, Yongxian, Wang, Yanlin, Xu, Yuming, Church, George M., Huang, He, Weng, Qinjie, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656711/
https://www.ncbi.nlm.nih.gov/pubmed/33176869
http://dx.doi.org/10.1186/s13045-020-00983-2