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A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
BACKGROUND: Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack of frank neuropathology from models based on common disease genes. Recent multi-cohort studies of postmortem h...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656729/ https://www.ncbi.nlm.nih.gov/pubmed/33172468 http://dx.doi.org/10.1186/s13024-020-00412-5 |