A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

BACKGROUND: Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack of frank neuropathology from models based on common disease genes. Recent multi-cohort studies of postmortem h...

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Detalles Bibliográficos
Autores principales: Preuss, Christoph, Pandey, Ravi, Piazza, Erin, Fine, Alexander, Uyar, Asli, Perumal, Thanneer, Garceau, Dylan, Kotredes, Kevin P., Williams, Harriet, Mangravite, Lara M., Lamb, Bruce T., Oblak, Adrian L., Howell, Gareth R., Sasner, Michael, Logsdon, Benjamin A., Carter, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656729/
https://www.ncbi.nlm.nih.gov/pubmed/33172468
http://dx.doi.org/10.1186/s13024-020-00412-5

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