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Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice

BACKGROUND: The risk of glaucoma increases significantly with age and exposure to elevated intraocular pressure, two factors linked with neuroinflammation. The complement cascade is a complex immune process with many bioactive end-products, including mediators of inflammation. Complement cascade act...

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Detalles Bibliográficos
Autores principales: Harder, Jeffrey M., Williams, Pete A., Braine, Catherine E., Yang, Hongtian S., Thomas, Jocelyn M., Foxworth, Nicole E., John, Simon W. M., Howell, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656757/
https://www.ncbi.nlm.nih.gov/pubmed/33176797
http://dx.doi.org/10.1186/s12974-020-02011-z