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Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice

BACKGROUND: The risk of glaucoma increases significantly with age and exposure to elevated intraocular pressure, two factors linked with neuroinflammation. The complement cascade is a complex immune process with many bioactive end-products, including mediators of inflammation. Complement cascade act...

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Detalles Bibliográficos
Autores principales:	Harder, Jeffrey M., Williams, Pete A., Braine, Catherine E., Yang, Hongtian S., Thomas, Jocelyn M., Foxworth, Nicole E., John, Simon W. M., Howell, Gareth R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656757/ https://www.ncbi.nlm.nih.gov/pubmed/33176797 http://dx.doi.org/10.1186/s12974-020-02011-z

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