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Clinical and mutational profiles of adult medulloblastoma groups

Adult medulloblastomas are clinically and molecularly understudied due to their rarity. We performed molecular grouping, targeted sequencing, and TERT promoter Sanger sequencing on a cohort of 99 adult medulloblastomas. SHH made up 50% of the cohort, whereas Group 3 (13%) was present in comparable p...

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Detalles Bibliográficos
Autores principales: Wong, Gabriel Chun-Hei, Li, Kay Ka-Wai, Wang, Wei-Wei, Liu, Anthony Pak-Yin, Huang, Queenie Junqi, Chan, Aden Ka-Yin, Poon, Manix Fung-Man, Chung, Nellie Yuk-Fei, Wong, Queenie Hoi-Wing, Chen, Hong, Chan, Danny Tat Ming, Liu, Xian-Zhi, Mao, Ying, Zhang, Zhen-Yu, Shi, Zhi-Feng, Ng, Ho-Keung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656770/
https://www.ncbi.nlm.nih.gov/pubmed/33172502
http://dx.doi.org/10.1186/s40478-020-01066-6