Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

BACKGROUND: Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNPs) in the ICD pathway are associated with the eff...

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Detalles Bibliográficos
Autores principales: Arai, Hiroyuki, Xiao, Yi, Loupakis, Fotios, Kawanishi, Natsuko, Wang, Jingyuan, Battaglin, Francesca, Soni, Shivani, Zhang, Wu, Mancao, Christoph, Salhia, Bodour, Mumenthaler, Shannon M, Weisenberger, Daniel J, Liang, Gangning, Cremolini, Chiara, Falcone, Alfredo, Millstein, Joshua, Lenz, Heinz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656952/
https://www.ncbi.nlm.nih.gov/pubmed/33172883
http://dx.doi.org/10.1136/jitc-2020-001714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656952/
https://www.ncbi.nlm.nih.gov/pubmed/33172883
http://dx.doi.org/10.1136/jitc-2020-001714

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