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Plasma-based microsatellite instability detection strategy to guide immune checkpoint blockade treatment

BACKGROUND: Microsatellite instability (MSI) represents the first pan-cancer biomarker approved to guide immune checkpoint blockade (ICB) treatment. However its widespread testing, especially outside of gastrointestinal cancer, is hampered by tissue availability. METHODS: An algorithm for detecting...

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Detalles Bibliográficos
Autores principales: Wang, Zhenghang, Zhao, Xiaochen, Gao, Chan, Gong, Jifang, Wang, Xicheng, Gao, Jing, Li, Zhongwu, Wang, Jie, Yang, Bo, Wang, Lei, Zhang, Bei, Zhou, Yifan, Wang, Dalei, Li, Xiaofang, Bai, Yuezong, Li, Jian, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656957/
https://www.ncbi.nlm.nih.gov/pubmed/33172882
http://dx.doi.org/10.1136/jitc-2020-001297