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Plasma-based microsatellite instability detection strategy to guide immune checkpoint blockade treatment
BACKGROUND: Microsatellite instability (MSI) represents the first pan-cancer biomarker approved to guide immune checkpoint blockade (ICB) treatment. However its widespread testing, especially outside of gastrointestinal cancer, is hampered by tissue availability. METHODS: An algorithm for detecting...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656957/ https://www.ncbi.nlm.nih.gov/pubmed/33172882 http://dx.doi.org/10.1136/jitc-2020-001297 |