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In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

The emergence and continued spread of SARS-CoV-2 have resulted in a public health emergency across the globe. The lack of knowledge on the precise mechanism of viral pathogenesis is impeding medical intervention. In this study, we have taken both in silico and in vitro experimental approaches to unr...

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Detalles Bibliográficos
Autores principales: Tiwari, Ritudhwaj, Mishra, Anurag R., Mikaeloff, Flora, Gupta, Soham, Mirazimi, Ali, Byrareddy, Siddappa N., Neogi, Ujjwal, Nayak, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657020/
https://www.ncbi.nlm.nih.gov/pubmed/33200027
http://dx.doi.org/10.1016/j.csbj.2020.11.005