IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation

Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive ability. We hypothesized that distinct CD8+ cytotoxic...

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Detalles Bibliográficos
Autores principales: Renavikar, Pranav S., Sinha, Sushmita, Brate, Ashley A., Borcherding, Nicholas, Crawford, Michael P., Steward-Tharp, Scott M., Karandikar, Nitin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657266/
https://www.ncbi.nlm.nih.gov/pubmed/33193343
http://dx.doi.org/10.3389/fimmu.2020.568630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657266/
https://www.ncbi.nlm.nih.gov/pubmed/33193343
http://dx.doi.org/10.3389/fimmu.2020.568630

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