Obesity Represses CYP2R1, the Vitamin D 25‐Hydroxylase, in the Liver and Extrahepatic Tissues

Low plasma level of 25‐hydroxyvitamin D (25‐OH‐D), namely vitamin D deficiency, is associated with obesity and weight loss improves 25‐OH‐D status. However, the mechanism behind obesity‐induced vitamin D deficiency remains unclear. Here, we report that obesity suppresses the expression of cytochrome...

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Detalles Bibliográficos
Autores principales: Elkhwanky, Mahmoud‐Sobhy, Kummu, Outi, Piltonen, Terhi T, Laru, Johanna, Morin‐Papunen, Laure, Mutikainen, Maija, Tavi, Pasi, Hakkola, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657391/
https://www.ncbi.nlm.nih.gov/pubmed/33210060
http://dx.doi.org/10.1002/jbm4.10397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657391/
https://www.ncbi.nlm.nih.gov/pubmed/33210060
http://dx.doi.org/10.1002/jbm4.10397

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