The Role of Kv7.2 in Neurodevelopment: Insights and Gaps in Our Understanding

Kv7.2 subunits encoded by the KCNQ2 gene constitute a critical molecular component of the M-current, a subthreshold voltage-gated potassium current controlling neuronal excitability by dampening repetitive action potential firing. Pathogenic loss-of-function variants in KCNQ2 have been linked to epi...

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Detalles Bibliográficos
Autores principales: Dirkx, Nina, Miceli, Francesco, Taglialatela, Maurizio, Weckhuysen, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657400/
https://www.ncbi.nlm.nih.gov/pubmed/33192566
http://dx.doi.org/10.3389/fphys.2020.570588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657400/
https://www.ncbi.nlm.nih.gov/pubmed/33192566
http://dx.doi.org/10.3389/fphys.2020.570588

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