A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1

In eukaryotes, ribonuclease H1 (RNase H1) is involved in the processing and removal of RNA/DNA hybrids in both nuclear and mitochondrial DNA. The enzyme comprises a C-terminal catalytic domain and an N-terminal hybrid-binding domain (HBD), separated by a linker of variable length, 115 amino acids in...

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Detalles Bibliográficos
Autores principales: González de Cózar, Jose M, Carretero-Junquera, Maria, Ciesielski, Grzegorz L, Miettinen, Sini M, Varjosalo, Markku, Kaguni, Laurie S, Dufour, Eric, Jacobs, Howard T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regular Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657459/
https://www.ncbi.nlm.nih.gov/pubmed/32589740
http://dx.doi.org/10.1093/jb/mvaa067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657459/
https://www.ncbi.nlm.nih.gov/pubmed/32589740
http://dx.doi.org/10.1093/jb/mvaa067

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