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Comparison of VEGF-A secretion from tumor cells under cellular stresses in conventional monolayer culture and microfluidic three-dimensional spheroid models

Vascular endothelial growth factor (VEGF) is a major cytokine in tumor biology affecting tumor survival, aggressiveness and pro-angiogenetic activities. In addition, cellular stresses often result in aggressive pro-angiogenetic behavior in tumors. For in vitro study, conventional monolayer cell cult...

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Detalles Bibliográficos
Autores principales: Sarkar, Sreerupa, Peng, Chien-Chung, Tung, Yi-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657494/
https://www.ncbi.nlm.nih.gov/pubmed/33175874
http://dx.doi.org/10.1371/journal.pone.0240833