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RNA structure prediction using positive and negative evolutionary information
Knowing the structure of conserved structural RNAs is important to elucidate their function and mechanism of action. However, predicting a conserved RNA structure remains unreliable, even when using a combination of thermodynamic stability and evolutionary covariation information. Here we present a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657543/ https://www.ncbi.nlm.nih.gov/pubmed/33125376 http://dx.doi.org/10.1371/journal.pcbi.1008387 |