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RNA structure prediction using positive and negative evolutionary information

Knowing the structure of conserved structural RNAs is important to elucidate their function and mechanism of action. However, predicting a conserved RNA structure remains unreliable, even when using a combination of thermodynamic stability and evolutionary covariation information. Here we present a...

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Detalles Bibliográficos
Autor principal: Rivas, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657543/
https://www.ncbi.nlm.nih.gov/pubmed/33125376
http://dx.doi.org/10.1371/journal.pcbi.1008387